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Meth and mdma

Methamphetamine and MDMA have been called safe drugs of abuse. Worldwide there is an increased consumption of these drugs, which has become a focus of research in South Africa.


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In vitro human studies show that the metabolism of most amphetamine-like 15 year old daughter dating 17 year old is regulated by the polymorphic cytochrome P isozyme CYP2D6. Two compounds, methamphetamine and 3,4-methylenedioxymethamphetamine MDMAwere selected as archetypes to discuss the translation and clinical ificance of in vitro to in vivo findings. Both compounds were chosen based on their differential interaction with CYP2D6 and their high abuse prevalence in society. The fraction of metabolic clearance regulated by CYP2D6 for both drugs is substantially lower than expected from in vitro studies.

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Mdma, methamphetamine, and cyp2d6 pharmacogenetics: what is clinically relevant?

In contact with the suspicious substance, the ampoule will change color. Compare then the color change with the color chart included in the leaflet.

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